C locus / TYR
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About this test
C locus / TYR (Tyrosinase) – Black Pigmentation Inhibitor
Possible Results: Homozygous Colored (does not affect pigmentation) / Heterozygous (affects black pigmentation).
Function: Tyrosinase catalyzes the first steps of melanin production (tyrosine → DOPA → dopaquinone). It is the gatekeeper enzyme of pigmentation. If TYR is non-functional, no melanin is produced (neither eumelanin nor pheomelanin)
In Ayam Cemani/Silkie Chicken: Any loss-of-function TYR alleles (the classic “c locus” alleles) eliminate pigmentation, producing white/cream plumage and pale skin regardless of EDN3 or MC1R status
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